Charcot–Marie–Tooth disease- (CMT), known also as Morbus Charcot-Marie-Tooth, is an inherited demyelinating disease of the peripheral nervous system. CMT is predominantly characterized by loss of muscle tissue and touch sensation, in the feet, ankles and legs as it progresses over time. As well as in the hands, wrists and arms in various types of the disease. Early and late onset forms occur with 'on and off' painful spasmodic muscular contractions that can be disabling when the disease activates.
