Scott Tipton, over at Comics101, agrees and points out some similar issues:
how does this affect CIVIL WAR? If Spidey's unmasking and subsequent switching of sides never happened, then did CIVIL WAR unfold differently? Are we ever going to be told that story?
Forget about CIVIL WAR, what about NEW AVENGERS? Clearly, none of those comics ever happened now, since a big part of that storyline was Peter, MJ and May moving into Stark Tower, and now that all has been wiped away. It surprises me that Quesada was willing to invalidate so much of the successful work done under his watch just to undo the marriage. Not to mention that the entire Stracyznski run has now also been rendered completely invalid, which is a real shame, as when his writing wasn't being dictated by outside influences (as we've since learned was the case on SINS PAST, for example), they made for some of the best Spidey stories in years.
And what about Venom? His earliest appearances came just after the Pete-MJ marriage, and if memory serves, often involved his threatening a married MJ; clearly, none of those stories took place, so Venom's backstory by definition must now be entirely new.
That whole business with the clones? Gone, one would assume, since so much of that involved Peter and MJ struggling to stay together in the face of Pete's identity crisis.
Even more striking is Harry's return, which lets us know exactly how many years' worth of Spidey stories no longer took place. Since the Harry we see here is definitely a single Harry, with no mention of wife Liz or son Norman, either Harry has divorced Liz in the new Spidey-continuity, or that marriage never took place either, which would set back Spider-Man's time-clock all the way back to 1976. That's a lot of Spider-history to have to ignore.
